Facilitated Nucleocytoplasmic Shuttling of the Ran Binding Protein RanBP1
نویسندگان
چکیده
منابع مشابه
Facilitated nucleocytoplasmic shuttling of the Ran binding protein RanBP1.
The Ran binding protein RanBP1 is localized to the cytosol of interphase cells. A leucine-rich nuclear export signal (NES) near the C terminus of RanBP1 is essential to maintain this distribution. We now show that RanBP1 accumulates in nuclei of cells treated with the export inhibitor, leptomycin B, and collapse of the nucleocytoplasmic Ran:GTP gradient leads to equilibration of RanBP1 across t...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2000
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.20.10.3510-3521.2000